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  5. Giovanni Ometto
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photo of Giovanni Ometto

Giovanni Ometto

Post-Doctoral Research Fellow in Image Processing

School of Health & Medical Sciences Department of Optometry and Visual Science

Contact details

  • +44 (0)20 7040 5060
  • Giovanni.Ometto@citystgeorges.ac.uk
  • @g_ometto
  • About
  • Publications

About

Overview

Giovanni was awarded a BSc in Bio-Engineering (2008) and MSc in Biomedical Engineering (2012) from the University of Padova (IT). In 2013 he worked in a company, developing and validating new image analysis algorithms for images of the conjunctiva and eye lids. In late 2013, he began working towards his PhD which he defended in May 2017. As a Marie Curie early stage researcher, his research was based at the Aarhus University Hospital (DK) in collaboration with the University of Lincoln (UK) and focused on image processing of retinal photographs and data analysis. Giovanni joined the Crabb Lab in 2017 as a post-doctoral research fellow and became the lab manager in 2020. His projects at City have been funded by Wellcome Trust, Fight For Sight, Diabetes UK, working in collaboration with industries such as Heidelberg Engineering and Topcon, some of the leading manufacturers of OCT acquisition devices. He is now with the UCL Insititute of Ophthalmology and London North West Healthcare NHS Trust, working as a Senior Data Analyst, but continues to collaborate with the Crabb Lab on several projects.

Qualifications

  • PhD, Aarhus University, Denmark, October 2013 - December 2016
  • Good Clinical Practice, National Institute for Health Research, United Kingdom
  • Biomedical Engineering BSc, MSc Eng, University of Padua, Italy

Employment

  • Honorary Research Fellow, Moorfields Eye Hospital NHS Foundation Trust, United Kingdom, November 2017 - present
  • Post-Doctoral Research Fellow, City, University of London, United Kingdom, February 2017 - present

Publications

Publications by category

Chapter

  • Al-Diri, B., Calivá, F., Chudzik, P., Ometto, G. and Habib, M. (2019). Diabetic retinopathy and maculopathy lesions. Computational Retinal Image Analysis (pp. 223-243). Elsevier. ISBN 9780081028162.

Conference papers and proceedings (16)

  • Montesano, G., Ometto, G., Crabb, D.P. and Gazzard, G. Five-year visual field outcomes of the HORIZON trial. .
  • Ometto, G., Montesano, G., Chakravarthy, U., Kee, F., Hogg, R.E. and Crabb, D.P. (2021). Fast 3-dimensional estimation of the Foveal Avascular Zone from OCTA. 2021 IEEE International Instrumentation and Measurement Technology Conference (I2MTC) 17-20 May.doi:10.1109/i2mtc50364.2021.9460087
  • Hogg, R.E., Montesano, G., Ometto, G., Higgins, B., Das, R., Chakravarthy, U.... Crabb, D. Early functional and imaging markers of retinal dysfunction prior to onset of clinically detectable diabetic retinopathy (DR). .
  • Ometto, G., Montesano, G., D'Antona, L., Bremner, F. and Crabb, D.P. A novel, automated measurement of spontaneous vein pulsation from infrared videos of the optic disc. .
  • Pohlmann, D., Terheyden, J.H., Berger, M., Ometto, G., Montesano, G., Neuber, F.... Pleyer, U. (2020). OCT-based automated vitreous inflammation score: a promising biomarker in dexamethasone implant treated uveitis patients. ARVO Annual Meeting 2020 3-7 May, Baltimore, USA.
  • Liu, X., Kale, A., Hui, B., Montesano, G., Capewell, N., Ometto, G.... Denniston, A.K. Test-retest Variability of Optical Coherence Tomography (OCT) and OCT Angiography in a Mobile OCT Module and level of Agreement with Conventional Table-top OCT. .
  • Ometto, G., Montesano, G., Terheyden, J.H. and Crabb, D.P. Quantification of two dimensional progression velocity in geographic atrophy and its relationship with autofluorescence at the borders. .
  • Coric, D., Ometto, G., Montesanto, G., Denniston, A., Keane, P., Balk, L.... Petzold, A. Vitreous haze as a novel marker for neurodegeneration in MS possibly indicating impairment of the retinal glymphatic system. .
  • Coric, D., Ometto, G., Montesanto, G., Denniston, A., Keane, P., Balk, L.... Crabb, D. Has the prevalence of uveitis in patients with multiple sclerosis been overestimated? .
  • Ometto, G., Moghul, I., Montesano, G., Hunter, A., Pontikos, N., Jones, P.R.... Crabb, D.P. ReLayer: a free, online tool for measuring retinal thickness based on a new automatic method for the segmentation of layers in OCT images. .
  • Jones, P.R. and Ometto, G. (2018). Degraded Reality: Using VR/AR to simulate visual impairments. 2018 IEEE Workshop on Augmented and Virtual Realities for Good (VAR4Good) 18 March.doi:10.1109/var4good.2018.8576885
  • Caliva, F., Hunter, A., Chudzik, P., Ometto, G., Antiga, L. and Al-Diri, B. (2017). A fluid-dynamic based approach to reconnect the retinal vessels in fundus photography. 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) 11-15 July.doi:10.1109/embc.2017.8036837
  • Chudzik, P., Al-Diri, B., Caliva, F., Ometto, G., Hunter, A., Styner, M.A.... Angelini, E.D. Learning deep similarity in fundus photography. SPIE Medical Imaging.doi:10.1117/12.2254286
  • Ometto, G., Erlandsen, M., Hunter, A. and Bek, T. The frequency of hemorrhages and microaneurysms in diabetic retinopathy is higher in the upper than the lower hemiretina. .
  • Ometto, G., Calivá, F., Al-Diri, B., Bek, T., Hunter, A., Styner, M.A.... Angelini, E.D. Automated detection of retinal landmarks for the identification of clinically relevant regions in fundus photography. SPIE Medical Imaging.doi:10.1117/12.2216488
  • Ometto, G., Bek, T., Al-Diri, B. and Hunter, A. An algorithm combining two lesion -detection methods of retinal microaneurysms for the reduction of human workload. .

Journal articles (42)

  • Balduzzi, E., Ometto, G., Bandello, F., Miserocchi, E. and Cicinelli, M.V. (2026). Unfolding the Pitchfork Sign in Type 2 Choroidal Neovascularization: A Longitudinal Analysis and 3-Dimensional Reconstructions. Ophthalmology Science, 6(7), pp. 101200-101200. doi:10.1016/j.xops.2026.101200

    [publisher’s website]

  • Mitchell, J., McIlwaine, G., Pead, E., Sloan, K., Ometto, G., MacGillivray, T.... Csincsik, L. (2026). Central and Peripheral Alterations of Retinal and Choroidal Vasculature in Multiple Sclerosis: Insights from Multimodal Imaging. Ophthalmology Science, 6(6), pp. 101192-101192. doi:10.1016/j.xops.2026.101192

    [publisher’s website]

  • Montesano, G., Ometto, G., Cheloni, R., Garway-Heath, D.F., Higgins, B.E., Crabb, D.P.... Freeman, M. (2026). Longitudinal Visual Field and Quality-of-Life Change in the Treatment for Advanced Glaucoma Study. Ophthalmology. doi:10.1016/j.ophtha.2026.04.020

    [publisher’s website]

  • Bek, T. and Ometto, G. (2026). Reproducibility in the identification of retinal positions on serial fundus photographs: Theory and limitations. Acta Ophthalmologica, 104(2), pp. 201-211. doi:10.1111/aos.17566

    [publisher’s website]

  • Montesano, G., Crabb, D.P., Garway-Heath, D.F., Wright, D.M., Konstantakopoulou, E., Nathwani, N.... Gazzard, G. (2026). Six-Year Rate of Visual Field Progression in the Laser in Glaucoma and Ocular Hypertension Trial. Ophthalmology, 133(2), pp. 169-177. doi:10.1016/j.ophtha.2025.09.023

    [publisher’s website]

  • Montesano, G., Crabb, D.P., Ometto, G. and Garway-Heath, D.F. (2026). Comparing the Rate of Retinal Nerve Fiber Layer and Visual Field Loss as Outcomes in Glaucoma Trials. Ophthalmology Glaucoma. doi:10.1016/j.ogla.2026.01.010

    [publisher’s website]

  • Solebo, A.L., Ang, M., Bellchambers, A., Chu, C.J., Denniston, A.K., Downie, L.E.... Xu, B. (2025). Development of the advised protocol for OCT study terminology and elements anterior segment OCT extension reporting guidelines (APOSTEL-AS): Study protocol. PLOS One, 20(11), pp. e0331272-e0331272. doi:10.1371/journal.pone.0331272

    [publisher’s website]

  • Fraser, A.S., Ang, M., Bellchambers, A., Chu, C.J., Denniston, A.K., Downie, L.E.... Solebo, A.L. (2025). Proposed Nomenclature for Landmarks in Anterior-Segment OCT. JAMA Ophthalmology, 143(9), pp. 749-749. doi:10.1001/jamaophthalmol.2025.2414

    [publisher’s website]

  • Montesano, G., Rabiolo, A., Garway-Heath, D.F., Fu, D.J., Gazzard, G., Ometto, G.... Khawaja, A.P. (2025). Association of Systemic Calcium Channel Blocker Use with Visual Field Progression in a Large Real-World Cohort from Glaucoma Clinics. Ophthalmology Glaucoma, 8(4), pp. 333-342. doi:10.1016/j.ogla.2025.03.002

    [publisher’s website]

  • Montesano, G., Rabiolo, A., Ometto, G., Crabb, D.P. and Garway-Heath, D.F. (2025). Relationship Between Intraocular Pressure and the True Rate of Functional and Structural Progression in the United Kingdom Glaucoma Treatment Study. Investigative Ophthalmology & Visual Science, 66(1), pp. 32-32. doi:10.1167/iovs.66.1.32

    [publisher’s website]

  • Reddingius, P.F., Kelly, S.R., Ometto, G., Garway-Heath, D.F. and Crabb, D.P. (2025). Does the Visual Field Improve After Initiation of Intraocular Pressure Lowering in the United Kingdom Glaucoma Treatment Study? American Journal of Ophthalmology, 269, pp. 346-354. doi:10.1016/j.ajo.2024.08.023

    [publisher’s website]

  • Montesano, G., Crabb, D.P., Wright, D.M., Rabiolo, A., Ometto, G. and Garway-Heath, D.F. (2024). Author Response: The Distribution of True Visual Field Progression Rates in Glaucoma. Translational Vision Science & Technology, 13(12), pp. 20-20. doi:10.1167/tvst.13.12.20

    [publisher’s website]

  • Fahy, E.T., Montesano, G., Garg, A., Vickerstaff, V., Konstantakopoulou, E., Gazzard, G.... Zhu, H. (2024). The Impact of Baseline Intraocular Pressure on Initial Treatment Response in the LiGHT Trial. Ophthalmology, 131(12), pp. 1366-1376. doi:10.1016/j.ophtha.2024.06.022

    [publisher’s website]

  • Evans, J.C., Ometto, G., Crabb, D.P. and Montesano, G. (2024). A Practical Framework for the Integration of Structural Data Into Perimetric Examinations. Translational Vision Science & Technology, 13(6), pp. 19-19. doi:10.1167/tvst.13.6.19

    [publisher’s website]

  • Cicinelli, M.V., Montesano, G., Berni, A., Scandale, P., Ometto, G., Introini, U.... Marchese, A. (2024). Photoreceptor Integrity in MEWDS: Longitudinal Structure-Function Correlations. Investigative Opthalmology & Visual Science, 65(4), pp. 28-28. doi:10.1167/iovs.65.4.28

    [publisher’s website]

  • Montesano, G., Crabb, D.P., Wright, D.M., Rabiolo, A., Ometto, G. and Garway-Heath, D.F. (2024). Estimating the Distribution of True Rates of Visual Field Progression in Glaucoma. Translational Vision Science & Technology, 13(4), pp. 15-15. doi:10.1167/tvst.13.4.15

    [publisher’s website]

  • Kaçar, S., Coric, D., Ometto, G., Montesano, G., Denniston, A.K., Keane, P.A.... Strijbis, E.M.M. (2023). Exploring Vitreous Haze as a Potential Biomarker for Accelerated Glymphatic Outflow and Neurodegeneration in Multiple Sclerosis: A Cross-Sectional Study. Brain Sciences, 14(1), pp. 36-36. doi:10.3390/brainsci14010036

    [publisher’s website]

  • Montesano, G., Redmond, T., Mulholland, P.J., Garway-Heath, D.F., Ometto, G., Romano, D.... Oddone, F. (2023). Spatial Summation in the Glaucomatous Macula: A Link With Retinal Ganglion Cell Damage. Investigative Opthalmology & Visual Science, 64(14), pp. 36-36. doi:10.1167/iovs.64.14.36

    [publisher’s website]

  • Pichi, F., Ometto, G., Invernizzi, A., Hay, S., Chaudhry, H., Aljneibi, S.... Neri, P. (2023). Automated quantification of uveitic keratic precipitates by use of anterior segment optical coherence tomography. Clinical & Experimental Ophthalmology, 51(8), pp. 790-798. doi:10.1111/ceo.14296

    [publisher’s website]

  • Montesano, G., Garway-Heath, D.F., Rabiolo, A., De Moraes, C.G., Ometto, G. and Crabb, D.P. (2023). Validating Trend-Based End Points for Neuroprotection Trials in Glaucoma. Translational Vision Science & Technology, 12(10), pp. 20-20. doi:10.1167/tvst.12.10.20

    [publisher’s website]

  • Montesano, G., Lazaridis, G., Ometto, G., Crabb, D.P. and Garway-Heath, D.F. (2023). Improving the Accuracy and Speed of Visual Field Testing in Glaucoma With Structural Information and Deep Learning. Translational Vision Science & Technology, 12(10), pp. 10-10. doi:10.1167/tvst.12.10.10

    [publisher’s website]

  • Montesano, G., Ometto, G., Ahmed, I.I.K., Ramulu, P.Y., Chang, D.F., Crabb, D.P.... Gazzard, G. (2023). Response to Comment on: Five-year visual field outcomes of the HORIZON trial. American Journal of Ophthalmology, 253, pp. 253-254. doi:10.1016/j.ajo.2023.05.013

    [publisher’s website]

  • Montesano, G., Ometto, G., Ahmed, I.I.K., Ramulu, P.Y., Chang, D.F., Crabb, D.P.... Gazzard, G. (2023). Five-Year Visual Field Outcomes of the HORIZON Trial. American Journal of Ophthalmology, 251, pp. 143-155. doi:10.1016/j.ajo.2023.02.008

    [publisher’s website]

  • Montesano, G., Mulholland, P.J., Garway-Heath, D.F., Evans, J., Ometto, G. and Crabb, D.P. (2023). Spatiotemporal summation of perimetric stimuli in healthy observers. Journal of Vision, 23(4), pp. 2-2. doi:10.1167/jov.23.4.2

    [publisher’s website]

  • MONTESANO, G., OMETTO, G., KING, A., GARWAY-HEATH, D.F. and CRABB, D.P. (2023). Two-Year Visual Field Outcomes of the Treatment of Advanced Glaucoma Study (TAGS). American Journal of Ophthalmology, 246, pp. 42-50. doi:10.1016/j.ajo.2022.09.011

    [publisher’s website]

  • Zicarelli, F., Ometto, G., Montesano, G., Motta, S., De Simone, L., Cimino, L.... Invernizzi, A. (2023). Objective Quantification of Posterior Segment Inflammation: Measuring Vitreous Cells and Haze Using Optical Coherence Tomography. American Journal of Ophthalmology, 245, pp. 134-144. doi:10.1016/j.ajo.2022.08.025

    [publisher’s website]

  • Liu, X., Kale, A.U., Ometto, G., Montesano, G., Sitch, A.J., Capewell, N.... Denniston, A.K. (2022). OCT Assisted Quantification of Vitreous Inflammation in Uveitis. Translational Vision Science & Technology, 11(1), pp. 3-3. doi:10.1167/tvst.11.1.3

    [publisher’s website]

  • Montesano, G., Garway-Heath, D.F., Ometto, G. and Crabb, D.P. (2021). Hierarchical Censored Bayesian Analysis of Visual Field Progression. Translational Vision Science & Technology, 10(12), pp. 4-4. doi:10.1167/tvst.10.12.4

    [publisher’s website]

  • Montesano, G., Ometto, G., Higgins, B.E., Das, R., Graham, K.W., Chakravarthy, U.... Hogg, R.E. (2021). Evidence for Structural and Functional Damage of the Inner Retina in Diabetes With No Diabetic Retinopathy. Investigative Opthalmology & Visual Science, 62(3), pp. 35-35. doi:10.1167/iovs.62.3.35

    [publisher’s website]

  • Allegrini, D., Montesano, G., Marconi, S., Rosso, N., Ometto, G., Raimondi, R.... Romano, M.R. (2021). A novel quantitative analysis method for idiopathic epiretinal membrane. PLOS ONE, 16(3), pp. e0247192-e0247192. doi:10.1371/journal.pone.0247192

    [publisher’s website]

  • Terheyden, J.H., Ometto, G., Montesano, G., Wintergerst, M.W.M., Langner, M., Liu, X.... Finger, R.P. (2021). Automated quantification of posterior vitreous inflammation: optical coherence tomography scan number requirements. Scientific Reports, 11(1). doi:10.1038/s41598-021-82786-0

    [publisher’s website]

  • Wintergerst, M.W.M., Liu, X., Terheyden, J.H., Pohlmann, D., Li, J.Q., Montesano, G.... Finger, R.P. (2021). Structural Endpoints and Outcome Measures in Uveitis. Ophthalmologica, 244(5), pp. 465-479. doi:10.1159/000517521

    [publisher’s website]

  • Montesano, G., Ometto, G., Higgins, B.E., Iester, C., Balaskas, K., Tufail, A.... Crabb, D.P. (2020). Structure–Function Analysis in Macular Drusen With Mesopic and Scotopic Microperimetry. Translational Vision Science & Technology, 9(13), pp. 43-43. doi:10.1167/tvst.9.13.43

    [publisher’s website]

  • Montesano, G., Ometto, G., Hogg, R.E., Rossetti, L.M., Garway-Heath, D.F. and Crabb, D.P. (2020). Revisiting the Drasdo Model: Implications for Structure-Function Analysis of the Macular Region. Translational Vision Science & Technology, 9(10), pp. 15-15. doi:10.1167/tvst.9.10.15

    [publisher’s website]

  • Ometto, G., Montesano, G., Sadeghi Afgeh, S., Lazaridis, G., Liu, X., Keane, P.A.... Denniston, A.K. (2020). Merging Information From Infrared and Autofluorescence Fundus Images for Monitoring of Chorioretinal Atrophic Lesions. Translational Vision Science & Technology, 9(9), pp. 38-38. doi:10.1167/tvst.9.9.38

    [publisher’s website]

  • Heikka, T., Ometto, G., Montesano, G., Rowe, S., Jansonius, N.M. and Crabb, D.P. (2020). Testing a phantom eye under various signal-to-noise ratio conditions using eleven different OCT devices. Biomedical Optics Express, 11(3), pp. 1306-1306. doi:10.1364/boe.383103

    [publisher’s website]

  • Coric, D., Ometto, G., Montesano, G., Keane, P.A., Balk, L.J., Uitdehaag, B.M.J.... Denniston, A.K. (2020). Objective quantification of vitreous haze on optical coherence tomography scans: no evidence for relationship between uveitis and inflammation in multiple sclerosis. European Journal of Neurology, 27(1), pp. 144-144. doi:10.1111/ene.14048

    [publisher’s website]

  • Ometto, G., Moghul, I., Montesano, G., Hunter, A., Pontikos, N., Jones, P.R.... Crabb, D.P. (2019). ReLayer: a Free, Online Tool for Extracting Retinal Thickness From Cross-Platform OCT Images. Translational Vision Science & Technology, 8(3), pp. 25-25. doi:10.1167/tvst.8.3.25

    [publisher’s website]

  • Chudzik, P., Al-Diri, B., Caliva, F., Ometto, G. and Hunter, A. (2018). Exudates Segmentation using Fully Convolutional Neural Network and Auxiliary Codebook. 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) pp. 770-773. doi:10.1109/embc.2018.8512354

    [publisher’s website]

  • Montesano, G., Way, C.M., Ometto, G., Ibrahim, H., Jones, P.R., Carmichael, R.... Denniston, A.K. (2018). Optimizing OCT acquisition parameters for assessments of vitreous haze for application in uveitis. Scientific Reports, 8(1). doi:10.1038/s41598-018-20092-y

    [publisher’s website]

  • Ometto, G., Assheton, P., Calivá, F., Chudzik, P., Al-diri, B., Hunter, A.... Bek, T. (2017). Spatial distribution of early red lesions is a risk factor for development of vision-threatening diabetic retinopathy. Diabetologia, 60(12), pp. 2361-2367. doi:10.1007/s00125-017-4424-y

    [publisher’s website]

  • Ometto, G., Erlandsen, M., Hunter, A. and Bek, T. (2017). The role of retinopathy distribution and other lesion types for the definition of examination intervals during screening for diabetic retinopathy. Acta Ophthalmologica, 95(4), pp. 400-404. doi:10.1111/aos.13334

    [publisher’s website]

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