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Professor David Crabb

Professor

School of Health & Medical Sciences Department of Optometry and Visual Science

Contact details

Personal links

About

Overview

David Crabb is Professor of Statistics and Vision Research and he joined City University London in 2005. David gained degrees in Mathematics and Statistics at Oxford and Sheffield before completing a PhD in Visual Science in 1996. Following a post-doctoral position at University College London and a lectureship in Nottingham, he took up his position at City University London in 2005.

Qualifications

  • PhD in Visual Science, 1996
  • MSc

Employment

  • Professor of Statistics and Vision Research, City, University London, United Kingdom, 2005 - present

Fellowships

  • Fellow, Royal Statistical Society

Teaching

Teaching

Modules taught on:

- OV1111 Optics1 and Quantitative Methods
- OV1013 Visual Optics and Mathematics
- OV3021 Research Studies
- OV3017 Eye Disease and Therapeutics
- OVM006 Glaucoma
- HRM003 Advanced Data Analysis

Research

Research Overview

David's research laboratory contains a lively mixture of vision scientists, ophthalmologists, psychologists, mathematicians and computer scientists. This research laboratory focuses on measurement in vision: visual fields, imaging, visual function and quality of life, and medical statistics. One of the main themes of his work in glaucoma is relating the different stages in the disease process to patient's visual disability.
www.staff.city.ac.uk/d.crabb

Research Areas

Measurement in vision: visual fields, imaging, image processing, visual function and quality of life, and medical statistics.

Grants

- 2013 £25,000
International Glaucoma Association
Project Grant (Charity)
Principal Investigator
Title: What type of visual field defects are hazardous for driving?

- 2012 £52,472
Fight for Sight
Project Grant (Charity)
Principal Investigator
Title: Proof of Concept forDetecting and monitoring age-related visual disease.
http://www.fightforsight.org.uk/project-display/items/231

- 2011 £114,000
Merck Investigator Studies Program
Project Grant (fEC)
Principal Investigator
Title: Measurements in glaucoma: What matters to the patient?

- 2011 £292,833
NIHR Post-Doctoral Research Fellowship Scheme
Fellowship (fEC)
Co-investigator and mentor for Dr Haogang Zhu (City University London)
Title: Complex data management, knowledge extraction and computerised clinical decision support for chronic disease Management

- 2011 £295,000
NIHR Health Services and Delivery Research (HS&DR) Program
Project Grant (fEC)
Principal Investigator
Title: Frequency of visual field testing when monitoring patients newly diagnosed with glaucoma http://www.netscc.ac.uk/hsdr/projdetails.php?ref=10-2000-68

- 2010 £245,000 (from a total of £1,480,000)
US National Institute for Health (NIH)
Project Grant (part fEC)
Co-Investigator with Dr B. Swanson (University of Indiana, US)
Title: Application of Psychophysical Models to Visual Disorders
Grant Number: NIH 2R01EY007716 - 19A2

Research assistants

Dr Fiona Glen
Dr Stefan Ceccon
Dr Nicholas Smith

Research students

Robyn Burton

Thesis title: Reading performance in glaucoma

Further information: (2009-)

Luke Saunders

Thesis title: Measuring visual function in glaucoma

Further information: (2011-)

Vera Moenter

Thesis title: Measuring visual function in glaucoma

Further information: (2011-)

Trishal Boodhna

Thesis title: Counting the cost of eye disease

Further information: (2012-)

Bruno Fidalgo

Thesis title: Screening for eye disease

Further information: (2012-)

Miss Angharad Hobby

Thesis title: Measuring Effects of long term anti-VEGF therapy on peripheral retinal function and structure

Further information: PhD start date Oct 2014; Second supervisor

Publications

Publications by category

Chapters (3)

  • (2025). An overview of quality of life and visual outcomes in AMD. In Progress in Brain Research (pp. 203-229). Elsevier. ISBN 9780443235894.
  • Crabb, D.P. (2015). Visual Fields. Glaucoma (pp. 109-124). Elsevier. ISBN 9780702051937.
  • Ceccon, S., Garway-Heath, D., Crabb, D.P. and Tucker, A. (2011). Ensembles of Bayesian Network Classifiers Using Glaucoma Data and Expertise. In Okun, O., Valentini, G. and Ré, M. (Eds.), Ensembles in Machine Learning Applications (pp. 133-150). Springer. ISBN 9783642229091.

Conference papers and proceedings (49)

  • Dunbar, H.M.P., Sassmannshausen, M., Behning, C., Thiele, S., Binns, A.M., Higgins, B.E.... Luhmann, U.F.O. (2022). Comparison of visual function in structurally defined sub-phenotypes of intermediate AMD: A MACUSTAR study report. ARVO Annual Meeting 2022 1-4 May, Denver, USA.
  • Montesano, G., McKendrick, A.M., Turpin, A., Brusini, P., Oddone, F., Fogagnolo, P.... Crabb, D.P. Do Additional Testing Locations Improve the Detection of Macular Perimetric Defects in Glaucoma? .doi:10.1016/j.ophtha.2021.06.012
  • Ometto, G., Montesano, G., Chakravarthy, U., Kee, F., Hogg, R.E. and Crabb, D.P. (2021). Fast 3-dimensional estimation of the Foveal Avascular Zone from OCTA. 2021 IEEE International Instrumentation and Measurement Technology Conference (I2MTC) 17-20 May.doi:10.1109/i2mtc50364.2021.9460087
  • Montesano, G., McKendrick, A.M., Turpin, A., Brusini, P., Oddone, F., Fogagnolo, P.... Crabb, D.P. (2021). Do additional testing locations improve the detection of macular perimetric defects in glaucoma? ARVO Annual Meeting 1-7 May, Virtual.
  • Dunbar, H., Behning, C., Taylor, D.J., Higgins, B.E., Montesano, G., Binns, A.M.... Luhmann, U.F.O. (2021). MACUSTAR cross-sectional data: Repeatability and discriminatory power of visual function tests. 2021 ARVO Annual Meeting 1-7 May, Online.
  • Wright, D.M., Konstantakopoulou, E., Montesano, G., Nathwani, N., Garg, A., Garway-Heath, D.F.... Gazzard, G. Visual Field Outcomes from LiGHT: Laser in Glaucoma and Ocular Hypertension, a multicentre, randomised controlled trial. .
  • Ometto, G., Montesano, G., D'Antona, L., Bremner, F. and Crabb, D.P. A novel, automated measurement of spontaneous vein pulsation from infrared videos of the optic disc. .
  • Montesano, G., Quigley, H.A. and Crabb, D.P. (2020). Minimising sample size for glaucoma neuroprotection trials by recruiting patients with low visual field test variability. ARVO Annual Meeting 2020 3-7 May, Baltimore, USA.
  • McDonald, L., Boodhna, T., Ajtony, C., Turnbull, P., Bourne, R.R.A. and Crabb, D.P. Illness perceptions in people newly diagnosed with glaucoma and ocular hypertension. .doi:10.1136/bjophthalmol-2018-313781
  • Khawaja, A.P., Chua, S., Hysi, P.G., Georgoulas, S., Currant, H., Fitzgerald, T.W.... Zheng, Y. Comparison of Associations with Different Macular Inner Retinal Thickness Parameters in a Large Cohort. .doi:10.1016/j.ophtha.2019.08.015
  • McDonald, L., Turnbull, P., Chang, L. and Crabb, D.P. Taking the strain? Impact of glaucoma on patients' informal caregivers. .doi:10.1038/s41433-019-0688-4
  • Modarelli, A.M., Montesano, G., Fogagnolo, P., Oddone, F., Lanzetta, P., Perdicchi, A.... Rossetti, L.M. Test-retest variability in anatomically defined visual field clusters with fundus perimetry. .
  • Romano, D., Montesano, G., Fogagnolo, P., McKendrick, A.M., Turpin, A., Oddone, F.... Rossetti, L.M. Effect of additional testing locations on the evaluation of macular perimetric defects in glaucoma. .
  • Ometto, G., Montesano, G., Terheyden, J.H. and Crabb, D.P. Quantification of two dimensional progression velocity in geographic atrophy and its relationship with autofluorescence at the borders. .
  • Higgins, B.E., Taylor, D.J., Bi, W., Binns, A.M. and Crabb, D.P. Novel computer-based tests for assessing performance in visually guided tasks in people with age-related macular degeneration: searching for everyday objects and detecting road signs. .
  • Jones, L., Cross, V., Crabb, D.P. and Shah, P. High-stakes ocular surgery through the eyes of the surgeon: Experiences of operating on 'only-eye' patients. .
  • Ometto, G., Moghul, I., Montesano, G., Hunter, A., Pontikos, N., Jones, P.R.... Crabb, D.P. ReLayer: a free, online tool for measuring retinal thickness based on a new automatic method for the segmentation of layers in OCT images. .
  • Ottobelli, L., Rossetti, L.M., Modarelli, A., Fogagnolo, P., Crabb, D.P. and Montesano, G. Structural mapping error in non-fundus perimetry. .
  • Bryan, S.R., Montesano, G., Rossetti, L.M., Fogagnolo, P., Oddone, F., McKendrick, A.M.... Crabb, D.P. Effect of fundus tracking on perimetric test retest-variability. .
  • Taylor, D.J., Jones, P.R., Smith, N.D., Binns, A.M. and Crabb, D.P. (2018). Measuring real-time anxiety during simulated mobility scenarios in people with non-neovascular age-related macular degeneration (AMD). ARVO 2018 3 May-29 April, Honolulu, Hawaii.
  • Montesano, G., Modarelli, A., Rossetti, L.M. and Crabb, D.P. (2018). Improving perimetric examination of the macular visual field using structural information. ARVO 2018 3 May-29 April, Honolulu, Hawaii.
  • Welikala, R.A., Fraz, M.M., Habib, M.M., Daniel-Tong, S., Yates, M., Foster, P.J.... Barman, S.A. (2017). Automated quantification of retinal vessel morphometry in the UK biobank cohort. 2017 Seventh International Conference on Image Processing Theory, Tools and Applications (IPTA) 28 November-1 December.doi:10.1109/ipta.2017.8310108
  • Way, C.M., Ibrahim, H., Bi, W., Carmichael, R., Crabb, D.P., Keane, P.A.... Denniston, A.K. Vitreous density estimation by Spectral Domain-OCT as a sensitive measure of uveitis activity: defining the technical limits of reliability. .
  • Taylor, D.J., Smith, N., Binns, A. and Crabb, D. Searching for objects in everyday scenes and recognising faces: measuring performance in people with dry age-related macular degeneration (AMD). .
  • Denniston, A.K., Zhu, H., Lee, A., Crabb, D.P., Tufail, A., Egan, C.A.... Johnston, R. The United Kingdom Diabetic Retinopathy Electronic Medical Record (UK DR EMR) Users Group:Report 2-real world data for diabetic macular edema and impact of cataract surgery from 20 United Kingdom hospital eye services. .
  • Garway-Heath, D.F., Zhu, H. and Crabb, D.P. Imaging improves the accuracy of visual field progression analysis in glaucoma: structure-guided ANSWERS. .
  • Boodhna, T., Saunders, L.J., Russel, R. and Crabb, D.P. Are we getting better at detecting glaucoma before the disease becomes advanced? An examination of trends in visual field severity at the time of diagnosis. .
  • Lascaratos, G., Garway-Heath, D.F., Russell, R.A., Crabb, D.P., Zhu, H., Hirn, C.... Suzuki, K. Intraocular pressure (IOP) measured with the Ocular Response Analyzer is a better predictor of glaucoma progression than Goldmann IOP in the United Kingdom Glaucoma Treatment Study (UKGTS). .
  • Zhu, H., Crabb, D.P. and Garway-Heath, D.F. More accurate modelling of visual field progression in glaucoma: ANSWERS. .
  • Smith, N.D., Zhu, H. and Crabb, D.P. Detecting vision loss in glaucoma using eye movement scanpaths recorded during free viewing of movies - a proof of principle study. .
  • Ceccon, S., Garway-Heath, D., Crabb, D.P., Tucker, A., Gama, J., Bradley, E.... Hollmén, J. The Dynamic Stage Bayesian Network: Identifying and Modelling Key Stages in a Temporal Process. .
  • Zhu, H., Crabb, D.P. and Artes, P.H. Improving the Classification of Abnormal Optic Discs Using Shape Analysis. .
  • Balian, C., Bergin, C., Sinapis, A., Sinapis, D., Moosavi, R., Verdon-Roe, G.M.... Flanagan, J.G. Structure Function Relationship in Glaucoma: Heidelberg Retinal Tomograph versus Standard Automated Perimetry, Frequency Doubling, Flicker Defined Form and Motion Detection. .
  • Sinapis, A., Bergin, C., Sinapis, D., Russell, R.A., Moosavi, R., Balian, C.... Garway-Heath, D.F. Perimetry Instrument Comparison Study: Between Test Variability of Four Threshold Perimetry Tests in Healthy and 'Glaucomatous' Eyes (Interim Analysis). .
  • Bergin, C., Sinapis, D., Sinapis, A., Moosavi, R., Verdon-Roe, G.M., Crabb, D.P.... Garway-Heath, D.F. Perimetry Instrument Comparison Study: Comparing the 'Screening' Strategies of Three Perimetry Devices to Discriminate Between Healthy and 'Glaucomatous' Eyes (Interim Results). .
  • Sinapis, D., Sinapis, A., Bergin, C., Moosavi, R., Russell, R.A., Verdon-Roe, G.M.... Garway-Heath, D.F. Perimetry Instrument Comparison Study: Comparing the Diagnostic Performance of Four Threshold Perimetry Tests to Discriminate Between Healthy and 'Glaucomatous' Eyes (Interim Analysis). .
  • Artes, P.H. and Crabb, D.P. Estimating Normative Limits of Heidelberg Retina Tomograph Optic Disc Rim Area with Quantile Regression. .doi:10.1167/iovs.08-3354
  • Zhu, H., Crabb, D.P. and Garway-Heath, D.F. A Bayesian Radial Basis Function Model to Link Retinal Structure and Visual Function in Glaucoma. .
  • Owen, V.M.F., Crabb, D.P., White, E.T., Viswanathan, A.C., Garway-Heath, D.F. and Hitchings, R.A. Glaucoma and fitness to drive: Using binocular visual fields to predict a milestone to blindness. .doi:10.1167/iovs.07-0877
  • Patterson, A.J., Garway-Heath, D.F. and Crabb, D.P. Improving the repeatability of topographic height measurements in confocal scanning laser imaging using maximum-likelihood deconvolution. .doi:10.1167/iovs.06-0191
  • Quaranta, L., Crabb, D.P., Fitzke, F.W. and Hitchings, R.A. Visual field progression characteristics in patients with normal tension glaucoma. .
  • CRABB, D.P., MCNAUGHT, A.I., FITZKE, F.W. and HITCHINGS, R.A. SPATIALLY ENHANCED MODELLING OF SENSITIVITY DECAY IN LOW-TENSION GLAUCOMA. .
  • CRABB, D.P., FITZKE, F.W., EDGAR, D.F. and MCNAUGHT, A.I. IMPROVING THE ANALYSIS OF GLAUCOMATOUS VISUAL-FIELD DATA WITH IMAGE-PROCESSING TECHNIQUES. .
  • CRABB, D.P., EDGAR, D.F. and FITZKE, F.W. A SPATIAL FILTER PROCESS TO DETECT THE LEVEL OF VARIABILITY WITHIN VISUAL-FIELD DATA. .
  • EDGAR, D.F., STEWARTJONES, J.H., CRABB, D.P., RUDNICKA, A.R., LAWRENSON, J.G., GUTTRIDGE, N.M.... OBRIEN, C. EFFECTS OF PILOCARPINE AND PROPINE ON PUPIL DIAMETER, AUTOMATED PERIMETRY AND LOGMAR ACUITY. .
  • GUTTRIDGE, N.M., EDGAR, D.F. and CRABB, D.P. THE EFFECT OF THE MENSTRUAL-CYCLE ON AUTOMATED PERIMETRY. .
  • RUDNICKA, A.R., STEELE, C.F., CRABB, D.P. and EDGAR, D.F. CLINICAL-EVALUATION OF THE ALLERGAN HUMPHREY ULTRASONIC BIOMETER. .
  • Montesano, G., Rossetti, L.M., McKendrick, A.M., Turpin, A., Fogagnolo, P., Oddone, F.... Crabb, D.P. Effect of fundus tracking on structure–function relationship in glaucoma. .doi:10.1136/bjophthalmol-2019-315070
  • Madjedi, K.M., Stuart, K.V., Chua, S.Y.L., Luben, R.N., Warwick, A., Pasquale, L.R.... Zheng, Y. The Association between Serum Lipids and Intraocular Pressure in 2 Large United Kingdom Cohorts. American Academy of Ophthalmology Annual Meeting New Orleans, Louisiana.doi:10.1016/j.ophtha.2022.04.023

Journal articles (297)

Media

  • Higgins, B., Taylor, D. and Crabb, D.(2019). Assessing everyday visual function in dry AMD – what matters to the person?

Professional activities

Consultancy

  • Moorfields Eye Hospital London
    Honorary consultant in Visual Science

Radio programme

  • BBC Health Check. BBC World Service (2014). http://www.bbc.co.uk/programmes/p02bmyt6