Dr Anuraag Bukkuri
Contact details
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About
Overview
Our lab develops and applies mathematical and philosophical tools to pose and address foundational questions at the interface of cancer, evolutionary ecology, and social science.
Qualifications
- PhD in Integrated Mathematical Oncology, University of South Florida, United States, 2024
- BA in Mathematics, University of Minnesota, United States, 2020
Employment
- Lecturer in Applied Mathematics, City St George's, University of London, United Kingdom, January 2026 - present
- Postdoctoral Associate, University of Pittsburgh School of Medicine, United States, 2024 - 2025
Publications
Publications by category
Journal articles (28)
- Bhattacharya, R., Bukkuri, A., Gatenby, R.A. and Brown, J.S. (2026). Cancer Evolvability Determines Therapy Outcomes. . doi:10.64898/2026.05.06.723143
- Bukkuri, A., McLaughlin, J., Duncan, A.W. and Stallaert, W. (2026). Life history enlightened therapies: cell cycle mapping to identify molecular targets to prevent hepatocellular carcinoma. Evolution, Medicine, and Public Health, 14(1), pp. 1-13. doi:10.1093/emph/eoag002
- Bukkuri, A., Streipert, S. and Kang, Y. (2026). Darwinian dynamics of Host-Pathogen interactions. Mathematical Biosciences and Engineering, 23(4), pp. 845-883. doi:10.3934/mbe.2026034
- Bhattacharya, R., Avdieiev, S.S., Bukkuri, A., Whelan, C.J., Gatenby, R.A., Tsai, K.Y.... Brown, J.S. (2025). The Hallmarks of Cancer as Eco-Evolutionary Processes. Cancer Discovery, 15(4), pp. 685-701. doi:10.1158/2159-8290.cd-24-0861
- Bukkuri, A., Andersson, S., Mazariegos, M.S., Brown, J.S., Hammarlund, E.U. and Mohlin, S. (2024). Cell types or cell states? An investigation of adrenergic and mesenchymal cell phenotypes in neuroblastoma. iScience, 27(12), pp. 111433-111433. doi:10.1016/j.isci.2024.111433
- Bukkuri, A. and Adler, F.R. (2024). Of criminals and cancer: The importance of social bonds and innate morality on cellular societies. Cells & Development, 180, pp. 203964-203964. doi:10.1016/j.cdev.2024.203964
- Bukkuri, A. (2024). Eco-evolutionary dynamics of structured populations in periodically fluctuating environments: a G function approach. Theory in Biosciences, 143(4), pp. 293-299. doi:10.1007/s12064-024-00424-5
- Carroll, C., Manaprasertsak, A., Boffelli Castro, A., van den Bos, H., Spierings, D.C.J., Wardenaar, R.... Hammarlund, E.U. (2024). Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation. Cancer Research Communications, 4(3), pp. 691-705. doi:10.1158/2767-9764.crc-23-0396
- Bukkuri, A., Pienta, K.J., Amend, S.R., Austin, R.H., Hammarlund, E.U. and Brown, J.S. (2023). The contribution of evolvability to the eco‐evolutionary dynamics of competing species. Ecology and Evolution, 13(10). doi:10.1002/ece3.10591
- Bukkuri, A., Pienta, K.J., Austin, R.H., Hammarlund, E.U., Amend, S.R. and Brown, J.S. (2023). A mathematical investigation of polyaneuploid cancer cell memory and cross-resistance in state-structured cancer populations. Scientific Reports, 13(1). doi:10.1038/s41598-023-42368-8
- Bukkuri, A. and Brown, J.S. (2023). Integrating eco‐evolutionary dynamics into matrix population models for structured populations: Discrete and continuous frameworks. Methods in Ecology and Evolution, 14(6), pp. 1475-1488. doi:10.1111/2041-210x.14111
- Bukkuri, A., Pienta, K.J., Hockett, I., Austin, R.H., Hammarlund, E.U., Amend, S.R.... Brown, J.S. (2023). Modeling cancer’s ecological and evolutionary dynamics. Medical Oncology, 40(4). doi:10.1007/s12032-023-01968-0
- Bukkuri, A. and Adler, F.R. (2023). Biomarkers or biotargets? Using competition to lure cancer cells into evolutionary traps. Evolution, Medicine, and Public Health, 11(1), pp. 264-276. doi:10.1093/emph/eoad017
- Venkatraman, G. and Bukkuri, A. (2022). Digest: Anther cones increase pollen release in buzz‐pollinated Solanum flowers*. Evolution, 76(9), pp. 2214-2215. doi:10.1111/evo.14584
- Bukkuri, A., Pienta, K.J., Austin, R.H., Hammarlund, E.U., Amend, S.R. and Brown, J.S. (2022). A life history model of the ecological and evolutionary dynamics of polyaneuploid cancer cells. Scientific Reports, 12(1). doi:10.1038/s41598-022-18137-4
- Bukkuri, A., Pienta, K.J., Austin, R.H., Hammarlund, E.U., Amend, S.R. and Brown, J.S. (2022). Stochastic models of Mendelian and reverse transcriptional inheritance in state-structured cancer populations. Scientific Reports, 12(1). doi:10.1038/s41598-022-17456-w
- Bukkuri, A., Gatenby, R.A. and Brown, J.S. (2022). GLUT1 production in cancer cells: a tragedy of the commons. npj Systems Biology and Applications, 8(1). doi:10.1038/s41540-022-00229-6
- Bhattacharya, R. and Bukkuri, A. (2022). Digest: Natural selection fluctuates at an extremely fine spatial scale inside a wild population of snapdragon plants *. Evolution, 76(5), pp. 1091-1093. doi:10.1111/evo.14453
- James, M.E., O'Brien, N.L.V. and Bukkuri, A. (2022). Digest: Stable phenotypes, fluid genotypes: how stochasticity impacts network evolution and speciation. Evolution, 76(4), pp. 821-823. doi:10.1111/evo.14452
- Bukkuri, A. and Brown, J.S. (2021). Evolutionary Game Theory: Darwinian Dynamics and the G Function Approach. Games, 12(4), pp. 72-72. doi:10.3390/g12040072
- Cunningham, J.J., Bukkuri, A., Brown, J.S., Gillies, R.J. and Gatenby, R.A. (2021). Coupled Source-Sink Habitats Produce Spatial and Temporal Variation of Cancer Cell Molecular Properties as an Alternative to Branched Clonal Evolution and Stem Cell Paradigms. Frontiers in Ecology and Evolution, 9. doi:10.3389/fevo.2021.676071
- Bukkuri, A. and Adler, F.R. (2021). Viewing Cancer Through the Lens of Corruption: Using Behavioral Ecology to Understand Cancer. Frontiers in Ecology and Evolution, 9. doi:10.3389/fevo.2021.678533
- Bukkuri, A., Andor, N. and Darcy, I.K. (2021). Applications of Topological Data Analysis in Oncology. Frontiers in Artificial Intelligence, 4. doi:10.3389/frai.2021.659037
- Bukkuri, A. (2020). The impact of infected T lymphocyte burst rate and viral shedding rate on optimal treatment scheduling in a human immunodeficiency virus infection. BIOMATH, 9(2). doi:10.11145/j.biomath.2020.08.173
- Bukkuri, A. (2020). Optimal control analysis of combined chemotherapy-immunotherapy treatment regimens in a PKPD cancer evolution model. BIOMATH, 9(1). doi:10.11145/j.biomath.2020.02.137
- Bukkuri, A. (2019). A mathematical model showing the potential of vitamin c to boost the innate immune response. Open Journal of Mathematical Sciences, 3(1), pp. 245-255. doi:10.30538/oms2019.0067
- Bukkuri, A. (2019). Optimal control analysis of combined anti-angiogenic and tumor immunotherapy. Open Journal of Mathematical Sciences, 3(1), pp. 349-357. doi:10.30538/oms2019.0078
- Bukkuri, A. (2019). A mathematical model of the effects of ascorbic acid on the onset of neurodegenerative diseases. Open Journal of Mathematical Sciences, 3(1), pp. 300-309. doi:10.30538/oms2019.0073