This course is for 2025/26 entry.
Genomic Medicine (Online) PGCert Course overview
Benefits of this course
You’ll learn how to interpret genomic data and how genomic data can be integrated into mainstream practice for the diagnosis of diseases such as neurological and cardiovascular disorders.
You’ll look at the role of genetics in disease and how genomic information can explain disease mechanisms and biology. We’ll also share examples of both common and rare diseases from across the entire healthcare spectrum to demonstrate how to interpret genomic data.
All modules studied on this course can also be studied on a modular basis towards your Professional Development (CPD).
When you join the course, you become part of an extensive learning community. You’ll connect with students and professionals from diverse backgrounds, creating opportunities for cross-cultural exchange, inter-professional learning and networking that extend beyond the course.
Award
You can select to apply for one of the available exit points for this course.
- Postgraduate Certificate (PGCert)
Who is this course for?
Our online PgCert is the perfect option for anyone interested or involved in Genomic Medicine including researchers, healthcare professionals, or biomedical scientists, that are looking for a flexible training course.
Structure
Students are required to complete four taught modules worth 15 credits each, to a total of 60 credits. Three of the modules are compulsory, with the final module chosen from two optional modules.
Modules run consecutively. Once a module opens, you will have ten weeks to complete it including the assessment. Completed module content will be available for you until the end of the course.
You will study on average 15 hours per week, which includes self-directed learning and preparing for assessments alongside learning materials. Depending on your level of genetics knowledge, you may need to spend less time, particularly for the fundamentals module.
2025/26 timetable (PDF)
Our modules can also be studied individually as part of Continuous Professional Development (CPD). View the above timetable for module running dates, and the apply tab for information on application deadlines and how to apply.
You can choose to upgrade the online PgCert to the in-person PgDip or MSc Genomic Medicine following successful completion of the course.
Modules
Core modules
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Fundamentals of Human Genetics and Genomics
Students undertaking this module will review the architecture of the human genome and the functional units embedded in it. Students will also cover aspects of gene regulation and chromatin structure and consider the importance of the epigenome. In addition, this module will cover DNA sequence variation and structural variation, exploring how this variation is “normal” but that sometimes it can be associated with disease. Students will learn about monogenic and multifactorial genetic disorders and the most appropriate methods for identifying causal and contributory variants. Students will also learn about some of the most common chromosomal abnormalities and the methods for detecting these in the laboratory. In essence, this module covers what the genome is, what variants can arise and how they arise, how best to identify these variants and what the clinical implications of these variants may be. This module is assessed with a 15 - 25 minute pre-recorded PowerPoint presentation of a case analysis.
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Genomics of Common and Rare Inherited Diseases
This module will initially explore the clinical presentation, diagnosis, management and treatment of a range of common and rare inherited diseases. The principles and practice of medical genetics and genomics, and the management and treatment of patients and their families will be discussed. In addition, the role of genomics in a care pathway will be examined, including the patient and family perspective. This module will explore the traditional and current approaches used to identify genes responsible for common and rare inherited diseases, focusing on the latter. Students will explore the analytical challenges in genomics, as applied to rare inherited diseases. The module will also cover key initiatives such as the development of genomic medicine services and the infrastructure supporting incorporation of genomic testing into the NHS. This module is assessed with an analysis of rare and common disease cases involving exome sequencing data.
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Variant Interpretation
This module will explore the genomic variants among individuals and populations, benign, pathological or of unknown significance, and the tools used by healthcare professionals to identify and interpret these and inform patient care. Students will cover tools used in variant interpretation, such as population databases, in silico analysis, functional data and phenotyping. Also introduced will be the national/international guidelines for genomic variant interpretation, and how variants are classified/weighted along these frameworks based on the tools learnt within the module. Beginning with an introduction to the identification of variants using next generation sequencing, students will cover genomic transcript nomenclature, classification under recognised guidelines, and patient case studies. This will be followed by coverage of a range of clinically employed variant interpretation tools, the ethics of variant interpretation, and end with applying these in the context of ACMG/ACGS frameworks, including pathogenicity, population analysis, as well as predictive, functional and segregational data. Brought together, this module will prepare students for understanding and applying variant interpretation in a clinical setting. This module is assessed with a Multidisciplinary Team Discussion (MDT) simulation.
Elective modules
Students can complete their remaining credits by selecting optional modules, studying alongside students from other courses.
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Genomics of Cardiovascular Disorders
This module explores the burden of cardiovascular disease and the underlying contribution of genetics to these diseases. Students will receive refresher sessions focused on cardiac function as well as being introduced to the key diagnostic tools used in cardiology. They will learn about the major arrhythmias and cardiomyopathies, which can lead to premature and sudden death. By studying genetic causes of lipid disorders students will understand the impact of rare and common genetic variants on the risk of coronary heart disease. The contribution of "big data" in disease diagnosis and the development of novel drugs will be discussed to demonstrate some of the benefits that genomics can offer to this group of diseases. Students will hear about the role and challenges of genetic counselling in inherited cardiac conditions. This module is assessed with a 2000 - 2500 word scenario-based essay.
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Genomics of Neurological Disorders (15 Credits)
This module explores the contribution of genomics to neurological disorders. Students will receive refresher sessions focussed on neuroanatomy and the development of the neurological system followed by an introduction to the key diagnostic tools used in neurology. They will learn about the major neurological disorder categories which have a high genetic contribution. The module will explore the value of the multidisciplinary team in phenotyping, interpretation of results, management and family communication. This module is assessed with a 1500 - 2000 word scenario-based essay.
Teaching and assessment
Our online Genomic Medicine PgCert combines flexibility, engagement, and cutting-edge technology to ensure students around the world can access high-quality education.
You will study on average 15 hours per week, which includes self-directed learning and preparing for assessments alongside learning materials. Depending on your level of genetics knowledge, you may need to spend less time, particularly for the fundamentals module.
Flexible scheduling
We understand the challenges of studying alongside other commitments in your life and we are excited to welcome a global audience as well. To accommodate our students, we offer a combination of synchronous (live) and asynchronous sessions (recorded sessions and many other directed-learning activities). The vast majority (at least 90%) of learning will be asynchronous meaning that you can complete the work at a time that suits you. Live classes are scheduled to accommodate students from diverse regions, including the Americas, Asia, Africa, and beyond.
Each module will include five live sessions set at the following suggested times 08.00, 11.00, 13.00, 16.00 and 17.00 (GMT/GMT+1). For those who cannot attend live, all sessions are recorded and made available for review at your convenience.
Self-paced learning
Modules will be designed with a clear study planner allowing you to progress at your own pace through the learning material. You will be able to see when there is an assignment coming up, allowing you to plan and manage your schedule. Miss a live session? No problem. Our platform ensures all course materials are accessible 24/7. This allows you to revisit lessons, catch up on missed classes, and study at a pace that suits you.
Interactive and engaging activities
Our online Genomic Medicine PgCert modules include a range of activities such as:
- Scenario-based assignments allowing you to apply what you’ve learned;
- Quizzes with in-built feedback to test your knowledge;
- Peer-to-peer discussion and group work to foster collaboration;
- Expert webinars and careers talks;
- Practical assessments that mirror real-world challenges.
Assessment
You can expect a mixture of:
- Pre-recorded presentation (case analysis)
- Analysis of rare and common disease cases involving exome sequencing data
- Multidisciplinary team discussion (MDT) simulation
- Scenario based essays
Your assessments will be formative and summative. This means some won’t count towards your final grade and you’ll have the chance to improve based on our feedback.
As this is a modular course there is no final exam. Instead, each module has one online assessment.
MOOCs
To support your learning outside of classes we’ve created three non-assessed Massive Online Open Courses (MOOCs). In preparation for our course, we recommend our students take The Genomics Era: The Future of Genetics in Medicine as it provides a basic grounding in genomics.
The course also offers training and resources on academic and research skills including refreshers in laboratory techniques and academic support for assessments.
Fees and funding
Fees for academic year 2025/26
Postgraduate Certificate (PGCert) PGCert
Part-time per year
Home/UK: £4,500
If you work for the NHS then you may be eligible for funding from NHS England for up to four taught modules. Applications for NHSE funding are now closed - please register your interest to be notified when more NHSE funding is released.
If you have any questions related to funding applications, please liaise with Dr George Wardley or visit the Genomics Education Programme website for more information.
In this tab you will find the financial information for this course of study, including details of financial support.
Additional costs
We do not expect students to incur any extra costs over and above those that we have advertised on the course page. To get the most from your studies, you will need your personal computer or laptop (Windows 10 or macOS) and an internet connection in your home. Find out more about technology requirements associated with online learning.
Career
Genomics is an area of rapid change. This course will upskill healthcare workers so they can apply and understand the relevance of genomic medicine to their work and enhance their career opportunities.
The course will also provide relevant knowledge and understanding applicable to careers in the pharmaceutical industry and academia.
Students can choose to upgrade the online PgCert to the in-person PgDip or MSc Genomic Medicine following successful completion of the course.
How to apply
Entry requirements
UK
To be considered for this course, you will need to:
- meet the entry criteria
- write a personal statement
- provide two suitable references
Undergraduate degree or equivalent
You should have or be expected to achieve, a minimum of a second class degree (2:2) in a relevant bioscience degree with sufficient genetics content. For healthcare graduates, a pass is required. All degrees must be awarded before 1 August on the year of entry.
We may invite you to interview if are unable to make a decision directly from your application.
Alternative professional qualifications, or previous related experience, may be considered and we encourage you to apply.
Intercalating students
Applicants who do not have an undergraduate degree but are current medical students who have successfully completed 360 credits (or equivalent) including at least 120 credits at Level 6 (or equivalent) of their medical degree are also eligible to apply.
International qualifications
We also accept qualifications from other countries for postgraduate study.
English language requirements
This is a Group 1 course.
Full details can be found on our English Language requirements webpages.
Application process
Before beginning your application please check the entry criteria of the course you wish to study to ensure you meet the required standards.
If you work for the NHS and wish to be considered for NHSE funding, please make this clear on your application.
Guidance on submitting an application can be found on our how to apply webpage.
Access our online application system
Select the relevant application link and create an account:
- Once you have created your account, you will be able to complete an application form and upload any relevant documents. You can save a partly completed form and return to it later. Please make sure you complete all sections. Please make sure that the information you provide is accurate, including the options you select in menus.
- Add pgadmissions@sgul.ac.uk to your address book to ensure you do not miss any important emails from us.
- When you have checked that your application is complete and accurate, click ‘submit’.
You can track your application through your online account.
If you are applying to study a module please note the following:
Applications for all modules close one month before the module start date.
If you wish to do more than one module, please use the application link for the module which occurs first. Please state in your personal statement exactly which modules you wish to do.
Current students on a Genomic Medicine standalone module at City St George's should contact genomics@sgul.ac.uk to enquire into studying further modules. Please do not use the above links.
September 2025 entry
Contact the postgraduate team
Telephone: +44 (0)20 7040 5000
Email: health@citystgeorges.ac.uk
Our academics
Your studies are supported by a team of committed and enthusiastic teachers and researchers, experts in their chosen field. On occasion we also work with external professionals to enhance your learning and appreciation of the wider subject.