Paul Roberts
Contact details
Personal links
About
Overview
Dr. Roberts is a Lecturer in the Department of Optometry and Visual Sciences, where he leads the Mathematical & Computational Ophthalmology (MaCO) Lab.
As a mathematical biologist, he uses mathematical models to explain and predict the behaviour of biological and physiological systems, with a particular emphasis on modelling the healthy and diseased eye and retina. His work is conducted in close collaboration with experimental biologists, biomedical scientists and clinicians.
Qualifications
- DPhil Systems Biology, University of Oxford, United Kingdom, October 2010 - June 2015
- Associate Fellow of the Higher Education Academy, University of Oxford, United Kingdom, July 2014
- MMath Mathematics, University of Oxford, United Kingdom, October 2006 - June 2010
Employment
- Lecturer, City St George’s, University of London, United Kingdom, July 2024 - present
- Centre Fellow, University of Birmingham, United Kingdom, October 2021 - July 2024
- Postdoctoral Research Fellow, University of Sussex, United Kingdom, January 2019 - March 2022
- Postdoctoral Research Fellow, University of Birmingham, United Kingdom, October 2015 - November 2018
Publications
Publications by category
Conference papers and proceedings (3)
- Roberts, P. and Ting, D. (2024). Mathematical Modelling for Predicting the Synergistic Effect of Antibiotic-Host Defence Peptide Combination Therapy for the Treatment of Bacterial Keratitis. 2024 ARVO Annual Meeting 5-9 May, Seattle, WA.
- Roberts, P., Andrews, J., Thomas, C., Jones, M.-.C. and Hill, L. (2023). Exploring the uptake and efficacy of topical Ranibizumab. 2023 ARVO Annual Meeting 23-27 April, New Orleans, LA.
- Jennifer, T., Dvoriashyna, M., Repetto, R., Crawshaw, J., Overby, D., Roberts, P.... Foss, A. (2023). Uveo-scleral flow: understanding the mechanism of unconventional drainage. 2023 ARVO Annual Meeting 23-27 April, New Orleans, LA.
Journal articles (16)
- Roberts, P. (2025). Perspective on running a mathematical and computational ophthalmology seminar series. Artificial Intelligence in Vision and Ophthalmology, 1(1). doi:10.35119/aivo.v1i1.153
- Roberts, P., Thomas, C.N., Bellamy Plaice, G., Roberts, J.A., Jones, M.-.C., Andrews, J.W.... Hill, L.J. (2025). Mathematical models of topically and intravitreally applied ranibizumab. Investigative Ophthalmology and Visual Science
- Tweedy, J.H., Dvoriashyna, M., Crawshaw, J.R., Overby, D.R., Repetto, R., Roberts, P.A.... Foss, A.J.E. (2025). A Model of the Mechanisms Underpinning Unconventional Aqueous Humor Outflow. Investigative Ophthalmology & Visual Science, 66(4), pp. 75-75. doi:10.1167/iovs.66.4.75
- Roberts, P.A. (2024). Advice to a Young Mathematical Biologist. Bulletin of Mathematical Biology, 86(5). doi:10.1007/s11538-024-01269-1
- Seifert, M., Roberts, P.A., Kafetzis, G., Osorio, D. and Baden, T. (2023). Birds multiplex spectral and temporal visual information via retinal On- and Off-channels. Nature Communications, 14(1). doi:10.1038/s41467-023-41032-z
- Hernandez, R.J., Roberts, P.A. and El-Bouri, W.K. (2023). Advancing treatment of retinal disease through in silico trials. Progress in Biomedical Engineering, 5(2), pp. 022002-022002. doi:10.1088/2516-1091/acc8a9
- Wang, X., Roberts, P.A., Yoshimatsu, T., Lagnado, L. and Baden, T. (2023). Amacrine cells differentially balance zebrafish color circuits in the central and peripheral retina. Cell Reports, 42(2), pp. 112055-112055. doi:10.1016/j.celrep.2023.112055
- Roberts, P.A. (2022). Inverse Problem Reveals Conditions for Characteristic Retinal Degeneration Patterns in Retinitis Pigmentosa Under the Trophic Factor Hypothesis. Frontiers in Aging Neuroscience, 14. doi:10.3389/fnagi.2022.765966
- Roberts, P.A. (2022). Mathematical models of retinitis pigmentosa: The trophic factor hypothesis. Journal of Theoretical Biology, 534, pp. 110938-110938. doi:10.1016/j.jtbi.2021.110938
- Zhou, M., Bear, J., Roberts, P.A., Janiak, F.K., Semmelhack, J., Yoshimatsu, T.... Baden, T. (2020). Zebrafish Retinal Ganglion Cells Asymmetrically Encode Spectral and Temporal Information across Visual Space. Current Biology, 30(15), pp. 2927-2942.e7. doi:10.1016/j.cub.2020.05.055
- Roberts, P.A., Huebinger, R.M., Keen, E., Krachler, A.-.M. and Jabbari, S. (2019). Mathematical model predicts anti-adhesion–antibiotic–debridement combination therapies can clear an antibiotic resistant infection. PLOS Computational Biology, 15(7), pp. e1007211-e1007211. doi:10.1371/journal.pcbi.1007211
- Roberts, P.A., Huebinger, R.M., Keen, E., Krachler, A.-.M. and Jabbari, S. (2018). Predictive modelling of a novel anti-adhesion therapy to combat bacterial colonisation of burn wounds. PLOS Computational Biology, 14(5), pp. e1006071-e1006071. doi:10.1371/journal.pcbi.1006071
- Roberts, P.A., Gaffney, E.A., Whiteley, J.P., Luthert, P.J., Foss, A.J.E. and Byrne, H.M. (2018). Predictive Mathematical Models for the Spread and Treatment of Hyperoxia-induced Photoreceptor Degeneration in Retinitis Pigmentosa. Investigative Opthalmology & Visual Science, 59(3), pp. 1238-1249. doi:10.1167/iovs.17-23177
- Roberts, P.A., Gaffney, E.A., Luthert, P.J., Foss, A.J.E. and Byrne, H.M. (2017). Mathematical models of retinitis pigmentosa: The oxygen toxicity hypothesis. Journal of Theoretical Biology, 425, pp. 53-71. doi:10.1016/j.jtbi.2017.05.006
- Roberts, P.A., Gaffney, E.A., Luthert, P.J., Foss, A.J.E. and Byrne, H.M. (2016). Retinal oxygen distribution and the role of neuroglobin. Journal of Mathematical Biology, 73(1), pp. 1-38. doi:10.1007/s00285-015-0931-y
- Roberts, P.A., Gaffney, E.A., Luthert, P.J., Foss, A.J.E. and Byrne, H.M. (2016). Mathematical and computational models of the retina in health, development and disease. Progress in Retinal and Eye Research, 53, pp. 48-69. doi:10.1016/j.preteyeres.2016.04.001
Professional activities
Editorial activity (3)
- Translational Vision Science & Technology (TVST), Editorial Board Member, August 2024 - present.
- Artificial Intelligence in Vision and Ophthalmology (AIVO), Editorial Board Member (EBM), June 2024 - present.
- Investigative Ophthalmology & Visual Science (IOVS), Guest Associate Editor (AE) and Creator of Mathematical and Computational Ophthalmology Special Issue, February 2023 - present.